But until Wednesday, it wasn't known that in the process of allowing nine earned runs in 3 1/3 innings, Reyes injured his right knee.
The Braves plan to place Reyes on the 15-day disabled list on Thursday. They are expected to fill his spot on the roster with Mike Dunn, who has allowed three hits and completed 3 1/3 scoreless innings for Triple-A Gwinnett this season.
"[Reyes'] knee is bad," Braves manager Bobby Cox said. "It really is. It's not an excuse. It's really bad."
Reyes said that he felt his knee pop while backing up the plate after Chase Headley delivered an RBI single in the 10-run fourth inning. Headley was the second batter the Padres sent to the plate after chasing Braves starter Jair Jurrjens.
Knowing that it was his job to eat up innings in the lopsided affair, Reyes continued to pitch and didn't exit until surrendering a Tony Gwynn two-run double with two outs in the seventh inning.
"I tried to walk it off and I didn't think there was anything to it, because it wasn't slipping or giving out," Reyes said. "But it was still pretty painful the whole outing. Yesterday was probably the worst day. Today, it feels a little better."
By the time the Braves realized the significance of Reyes' knee ailment, left-hander Jonny Venters had already completed a side session for Triple-A Gwinnett on Thursday afternoon. Venters, who tossed 4 2/3 innings in a start on Monday, would have likely been called up if he would have been able to at least be available to pitch in relief during Thursday's series finale in San Diego.